dna tests

Border Collies

C.E.A Collie Eye Anomaly
A congenital, inherited eye condition that can vary from mild, to severe, causing blindness.
Recessive, genetical condition. Both parents must carry (or have) the condition to produce it in pups. A ‘normal’ parent will not produce it but could produce more carriers if mated to a carrier or affected.

Goniodysgenesis  (GLC)
An abnormality within the eye associated with primary closed angle glaucoma. The fluid in the eye does not drain properly,
Recessive, genetical condition. Both parents must carry (or have) the condition to produce it in pups. A ‘normal’ parent will not produce it but could produce carriers if mated to a carrier or affected.

T.N.S. Trapped Neutrophil Syndrome
An immune system disease where the white blood cells produced by the bone marrow become “trapped” and cannot be effectively released into the bloodstream.  The dog is unable to fight infection will become ill & eventually die from infections.
Recessive, genetical condition. Both parents must carry (or have) the condition to produce it in pups. A ‘normal’ parent will not produce it but could produce more carriers if mated to a carrier or affected.


C.L. Ceroid Lipofuscinosis
Also known as storage disease is a rare disease which affects the nerve cells of the body.  Most symptoms do not appear until the age of 18 months, but then increase rapidly with dogs rarely living past the age of 2 ½ years.  Symptoms, which include apprehension, abnormal gait & demented behaviour increase rapidly after onset.
Recessive, genetical condition. Both parents must carry (or have) the condition to produce it in pups. A ‘normal’ parent will not produce it but could produce more carriers if mated to a carrier or affected.


I.G.S. Vitamin B12 Deficiency
A genetic disorder by which the vitamin B12, fails to be absorbed from the intestine. Lack of B12 leads to changes in the hematopoietic system and to neurological symptoms due to irreversible damage of the brain and nervous system. Symptoms include anorexia, lethargy and failure to gain weight
Recessive, genetical condition. Both parents must carry (or have) the condition to produce it in pups. A ‘normal’ parent will not produce it but could produce more carriers if mated to a carrier or affected.


S.N. Sensory Neuropathy
A neurological disease caused by the progressive degeneration of sensory and motor nerve cells. The onset of the disease occurs between 2 to 7 months of age and quality of life is severely affected, Symptoms include knuckling of the feet, self-mutilation wounds and incoordination of gait, with a progressive loss of sensation occurring in all limbs.
Recessive, genetical condition. Both parents must carry (or have) the condition to produce it in pups. A ‘normal’ parent will not produce it but could produce more carriers if mated to a carrier or affected.


M.D.R.1 Multi Drug Resistance gene

The MDR1 gene is responsible for ensuring that the P-glycoprotein functions normally by protecting the body from toxins.  In MDR1 affected dogs the function is M.D.R.1 Multi Drug Resistance gene compromised and therefore toxins (from environment or drugs etc) may leak into the major organs.
Recessive, genetical condition. Both parents must carry (or have) the condition to produce it in pups. A ‘normal’ parent will not produce it but could produce more carriers if mated to a carrier or affected.


Dental Hypomineralization (DH) is also known as Raine Syndrome.
 DH is an autosomal recessive disorder that is known to affect Border Collies. This disorder is characterized by extreme wear of the teeth that can be very painful. The only way to treat this condition is by extracting worn teeth
Recessive, genetical condition. Both parents must carry (or have) the condition to produce it in pups. A ‘normal’ parent will not produce it but could produce more carriers if mated to a carrier or affected

All the above can be tested using either swabs or blood and most of the tests are available at several laboratories around the world at varying costs.

The P.B.H.F. run regular discounted clinics for all of the DNA tests above.